Organic chemistry in nanomedicine
I am an organic chemist working in biomedical research, this page provides an overview of my training, work experience, and output.
My scientific foundation consists of a training in organic chemistry (B.ASc.) and molecular engineering (M.Sc.), both acquired in Eindhoven, the Netherlands. During my bachelor, I completed several research internships, including establishing analytical methods to analyze [18F]-FDG at GE Healthcare, and developing supramolecular membranes for hemodialysis in the group of Dr. Dankers at the Eindhoven University of Technology (TU/e).
During my master and Ph.D studies, also at the TU/e, I focused on biomimetic supramolecular chemistry in the group of Dr. E.W. Meijer. Throughout this period, I developed synthetic chemical systems emulating important aspects of biochemical systems, such as autocatalysis, multivalent binding, and stimulus-responsiveness. As a result of this work, I acquired expertise in the synthesis and characterization of complex organic molecules and their self-assembly into nanostructures. Besides conducting research, I taught several chemistry courses and supervised bachelor and master students. I also enrolled in a variety of courses, focusing on academic writing, biocatalysis, computational chemistry, and scientific integrity.
Intrigued by the biomedical aspects of this work, I decided to apply my scientific expertise to translational nanomedicine. In the fall of 2017, I started as postdoctoral fellow in the Mulder Lab at the Icahn School of Medicine at Mount Sinai in New York. During this period, I became proficient in the development and characterization of nanotherapeutics targeting the innate immune system to treat cancer, cardiovascular disease, stroke, and atherosclerosis. I also became responsible for all radiosyntheses, which I perform in collaboration with the Reiner lab at the Memorial Sloan Kettering Cancer Center.
After a one-year postdoc, I got promoted to the rank of Instructor, expanding my responsibilities to include the daily supervision of the Mulder lab and training both master and graduate students. I also became involved in the hiring of new personnel, writing grant proposals, chairing group meetings, organizing symposia, and maintaining collaborations. Lastly, I increased my experimental skills in biomedical research, including completing a course on working with rodent test animals, performing cellular assays, and assisting with nuclear imaging.